Pincus Lab

Washington University School of Medicine

Department of Developmental Biology
and Department of Genetics

For further information, consult Google Scholar or PubMed.

  1. Lambert A, Vanhecke A, Archetti A, Holden S, Schaber F, Pincus Z, Laub MT, Goley E & Manley S.
    Constriction Rate Modulation Can Drive Cell Size Control and Homeostasis in C. crescentus.
    iScience (2018). pubmed | journal
  2. Galimov ER, Pryor RE, Poole SE, Benedetto A, Pincus Z & Gems D.
    Coupling of Rigor Mortis and Intestinal Necrosis during C. elegans Organismal Death.
    Cell Rep (2018). pubmed | journal
  3. Gaertner F, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa-Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher RT, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt M & Massberg S.
    Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria.
    Cell (2017). pubmed | journal
  4. Inukai S, Pincus Z, de Lencastre A & Slack FJ.
    A microRNA feedback loop regulates global microRNA abundance during aging.
    RNA (2017). pubmed | journal
  5. Pittman WE, Sinha DB, Zhang WB, Kinser HE & Pincus Z.
    A simple culture system for long-term imaging of individual C. elegans.
    Lab Chip (2017). pubmed | journal
  6. Zhao Y, Gilliat AF, Ziehm M, Turmaine M, Wang H, Ezcurra M, Yang C, Phillips G, McBay D, Zhang WB, Partridge L, Pincus Z & Gems D.
    Two forms of death in ageing Caenorhabditis elegans.
    Nat Commun (2017). pubmed | journal
  7. Zhang WB, Sinha DB, Pittman WE, Hvatum E, Stroustrup N & Pincus Z.
    Extended Twilight among Isogenic C. elegans Causes a Disproportionate Scaling between Lifespan and Health.
    Cell Systems (2016). pubmed | journal
  8. Weicksel SE, Mahadav A, Moyle M, Cipriani PG, Kudron M, Pincus Z, Bahmanyar S, Abriola L, Merkel J, Gutwein M, Fernandez AG, Piano F, Gunsalus KC & Reinke V.
    A novel small molecule that disrupts a key event during the oocyte-to-embryo transition in C. elegans.
    Development (2016). pubmed | journal
  9. Kinser HE & Pincus Z.
    High-throughput screening in the C. elegans nervous system.
    Mol Cell Neurosci (2016). pubmed | journal
  10. Pincus Z, Mazer TC & Slack FJ.
    Autofluorescence as a measure of senescence in C. elegans: look to red, not blue or green.
    Aging (2016). pubmed | journal
  11. Pincus Z.
    Ageing: A stretch in time.
    Nature (2016). pubmed | journal
  12. Zhang WB & Pincus Z.
    Predicting all-cause mortality from basic physiology in the Framingham Heart Study.
    Aging Cell (2016). pubmed | journal
  13. Martinez LE, Hardcastle JM, Wang J, Pincus Z, Tsang J, Hoover TR, Bansil R & Salama NR.
    Helicobacter pylori strains vary cell shape and flagellum number to maintain robust motility in viscous environments.
    Mol Microbiol (2015). pubmed | journal
  14. Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, Svoronos A, Braddock DT, Glazer PM, Engelman DM, Saltzman WM & Slack FJ.
    MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.
    Nature (2015). pubmed | journal
  15. Sycuro LK, Rule CS, Petersen TW, Wyckoff TJ, Sessler T, Nagarkar DB, Khalid F, Pincus Z, Biboy J, Vollmer W & Salama NR.
    Flow cytometry-based enrichment for cell shape mutants identifies multiple genes that influence Helicobacter pylori morphology.
    Mol Microbiol (2013). pubmed | journal
  16. Coburn C, Allman E, Mahanti P, Benedetto A, Cabreiro F, Pincus Z, Matthijssens F, Araiz C, Mandel A, Vlachos M, Edwards S, Fischer G, Davidson A, Pryor RE, Stevens A, Slack FJ, Tavernarakis N, Braeckman BP, Schroeder FC, Nehrke K & Gems D.
    Anthranilate Fluorescence Marks a Calcium-Propagated Necrotic Wave That Promotes Organismal Death in C. elegans.
    PLoS Biol (2013). pubmed | journal
  17. Tevy MF, Giebultowicz J, Pincus Z, Mazzoccoli G & Vinciguerra M.
    Aging signaling pathways and circadian clock-dependent metabolic derangements.
    Trends Endocrinol Metab (2013). pubmed | journal
  18. Yam PT, Pincus Z, Gupta GD, Bashkurov M, Charron F, Pelletier L & Colman DR.
    N-cadherin relocalizes from the periphery to the center of the synapse after transient synaptic stimulation in hippocampal neurons.
    PLoS ONE (2013). pubmed | journal
  19. Sycuro LK, Wyckoff TJ, Biboy J, Born P, Pincus Z, Vollmer W & Salama NR.
    Multiple Peptidoglycan Modification Networks Modulate Helicobacter pylori{\textquoteright}s Cell Shape, Motility, and Colonization Potential.
    PLoS Pathog (2012). pubmed | journal
  20. Pincus Z, Smith-Vikos T & Slack FJ.
    MicroRNA Predictors of Longevity in Caenorhabditis elegans
    PLoS Genet (2011). pubmed | journal
  21. Zhou KI, Pincus Z & Slack FJ.
    Longevity and stress in Caenorhabditis elegans.
    Aging (2011). pubmed | journal
  22. Dye NA, Pincus Z, Fisher IC, Shapiro L & Theriot JA.
    Mutations in the nucleotide binding pocket of MreB can alter cell curvature and polar morphology in Caulobacter.
    Mol Microbiol (2011). pubmed | journal
  23. de Lencastre A, Pincus Z, Zhou K, Kato M, Lee SS & Slack FJ.
    MicroRNAs both promote and antagonize longevity in C. elegans.
    Curr Biol (2010). pubmed | journal
  24. Sycuro LK, Pincus Z, Gutierrez KD, Biboy J, Stern CA, Vollmer W & Salama NR.
    Peptidoglycan crosslinking relaxation promotes Helicobacter pylori{\textquoteright}s helical shape and stomach colonization.
    Cell (2010). pubmed | journal
  25. Pincus Z & Slack FJ.
    Developmental biomarkers of aging in Caenorhabditis elegans.
    Dev Dyn (2010). pubmed | journal
  26. Kato M, de Lencastre A, Pincus Z & Slack FJ.
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development.
    Genome Biol (2009). pubmed | journal
  27. Keren K, Pincus Z, Allen GM, Barnhart EL, Marriott G, Mogilner A & Theriot JA.
    Mechanism of shape determination in motile cells.
    Nature (2008). pubmed | journal
  28. Pincus Z & Slack FJ.
    Transcriptional (dys)regulation and aging in Caenorhabditis elegans.
    Genome Biol (2008). pubmed | journal
  29. Lacayo CI, Pincus Z, VanDuijn MM, Wilson CA, Fletcher DA, Gertler FB, Mogilner A & Theriot JA.
    Emergence of large-scale cell morphology and movement from local actin filament growth dynamics.
    PLoS Biol (2007). pubmed | journal
  30. Pincus Z & Theriot JA.
    Comparison of quantitative methods for cell-shape analysis.
    J Microscopy (2007). pubmed | journal
  31. Dye NA, Pincus Z, Theriot JA, Shapiro L & Gitai Z.
    Two independent spiral structures control cell shape in Caulobacter.
    Proc Natl Acad Sci USA (2005). pubmed | journal
  32. Kaufer D, Ogle WO, Pincus Z, Clark KL, Nicholas AC, Dinkel KM, Dumas TC, Ferguson D, Lee AL, Winters MA & Sapolsky RM.
    Restructuring the neuronal stress response with anti-glucocorticoid gene delivery.
    Nat Neurosci (2004). pubmed | journal
  33. O’Connor MJ, Buckeridge DL, Choy M, Crubezy M, Pincus Z & Musen MA.
    BioSTORM: a system for automated surveillance of diverse data sources.
    Proc AMIA Symp (2003). pubmed | journal
  34. Pincus Z & Musen MA.
    Contextualizing heterogeneous data for integration and inference.
    Proc AMIA Symp (2003). pubmed | journal